Male-lineage transmission of an acquired metabolic phenotype induced by grand-paternal obesity

OBJECTIVE: Parental obesity can induce metabolic phenotypes in offspring independent of the inherited DNA sequence. Here we asked whether such non-genetic acquired metabolic traits can be passed on to a second generation that has never been exposed to obesity, even as germ cells. METHODS: We examine...

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Detalhes bibliográficos
Publicado no:Mol Metab
Main Authors: Cropley, Jennifer E., Eaton, Sally A., Aiken, Alastair, Young, Paul E., Giannoulatou, Eleni, Ho, Joshua W.K., Buckland, Michael E., Keam, Simon P., Hutvagner, Gyorgy, Humphreys, David T., Langley, Katherine G., Henstridge, Darren C., Martin, David I.K., Febbraio, Mark A., Suter, Catherine M.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
Assuntos:
Brief Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5021672/
https://ncbi.nlm.nih.gov/pubmed/27656407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2016.06.008
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