Optogenetic activation of leptin- and glucose-regulated GABAergic neurons in dorsomedial hypothalamus promotes food intake via inhibitory synaptic transmission to paraventricular nucleus of hypothalamus

OBJECTIVE: The dorsomedial hypothalamus (DMH) has been considered an orexigenic nucleus, since the DMH lesion reduced food intake and body weight and induced resistance to diet-induced obesity. The DMH expresses feeding regulatory neuropeptides and receptors including neuropeptide Y (NPY), cocaine-...

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Detalhes bibliográficos
Publicado no:Mol Metab
Main Authors: Otgon-Uul, Zesemdorj, Suyama, Shigetomo, Onodera, Hiroshi, Yada, Toshihiko
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
Assuntos:
Brief Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5021668/
https://ncbi.nlm.nih.gov/pubmed/27656408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2016.06.010
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