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Scheduled Intermittent Screening with Rapid Diagnostic Tests and Treatment with Dihydroartemisinin-Piperaquine versus Intermittent Preventive Therapy with Sulfadoxine-Pyrimethamine for Malaria in Pregnancy in Malawi: An Open-Label Randomized Controlled Trial

BACKGROUND: In Africa, most plasmodium infections during pregnancy remain asymptomatic, yet are associated with maternal anemia and low birthweight. WHO recommends intermittent preventive therapy in pregnancy with sulfadoxine-pyrimethamine (IPTp-SP). However, sulfadoxine-pyrimethamine (SP) efficacy...

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Udgivet i:PLoS Med
Main Authors: Madanitsa, Mwayiwawo, Kalilani, Linda, Mwapasa, Victor, van Eijk, Anna M., Khairallah, Carole, Ali, Doreen, Pace, Cheryl, Smedley, James, Thwai, Kyaw-Lay, Levitt, Brandt, Wang, Duolao, Kang’ombe, Arthur, Faragher, Brian, Taylor, Steve M., Meshnick, Steve, ter Kuile, Feiko O.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5021271/
https://ncbi.nlm.nih.gov/pubmed/27622558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.1002124
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