Priming Vaccination With Influenza Virus H5 Hemagglutinin Antigen Significantly Increases the Duration of T cell Responses Induced by a Heterologous H5 Booster Vaccination

Background. Influenza A(H5N1) virus and other avian influenza virus strains represent major pandemic threats. Like all influenza A virus strains, A(H5N1) viruses evolve rapidly. Innovative immunization strategies are needed to induce cross-protective immunity. Methods. Subjects primed with clade 1 H...

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Detalhes bibliográficos
Publicado no:J Infect Dis
Main Authors: Hoft, Daniel F., Lottenbach, Kathleen, Goll, Johannes B., Hill, Heather, Winokur, Patricia L., Patel, Shital M., Brady, Rebecca C., Chen, Wilbur H., Edwards, Kathryn, Creech, C. Buddy, Frey, Sharon E., Blevins, Tamara P., Salomon, Rachelle, Belshe, Robert B.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Major Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5021235/
https://ncbi.nlm.nih.gov/pubmed/27443611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiw310
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