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Reductive Umpolung of Carbonyl Derivatives with Visible‐Light Photoredox Catalysis: Direct Access to Vicinal Diamines and Amino Alcohols via α‐Amino Radicals and Ketyl Radicals

Visible‐light‐mediated photoredox‐catalyzed aldimine–aniline and aldehyde–aniline couplings have been realized. The reductive single electron transfer (SET) umpolung of various carbonyl derivatives enabled the generation of intermediary ketyl and α‐amino radical anions, which were utilized for the s...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Fava, Eleonora, Millet, Anthony, Nakajima, Masaki, Loescher, Sebastian, Rueping, Magnus
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5021176/
https://ncbi.nlm.nih.gov/pubmed/27136443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201511235
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