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Spatiotemporal analysis of putative notochordal cell markers reveals CD24 and keratins 8, 18, and 19 as notochord‐specific markers during early human intervertebral disc development

In humans, the nucleus pulposus (NP) is composed of large vacuolated notochordal cells in the fetus but, soon after birth, becomes populated by smaller, chondrocyte‐like cells. Although animal studies indicate that notochord‐derived cells persist in the adult NP, the ontogeny of the adult human NP c...

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Bibliografiske detaljer
Udgivet i:J Orthop Res
Main Authors: Rodrigues‐Pinto, Ricardo, Berry, Andrew, Piper‐Hanley, Karen, Hanley, Neil, Richardson, Stephen M., Hoyland, Judith A.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5021113/
https://ncbi.nlm.nih.gov/pubmed/26910849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jor.23205
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