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Spatiotemporal analysis of putative notochordal cell markers reveals CD24 and keratins 8, 18, and 19 as notochord‐specific markers during early human intervertebral disc development

In humans, the nucleus pulposus (NP) is composed of large vacuolated notochordal cells in the fetus but, soon after birth, becomes populated by smaller, chondrocyte‐like cells. Although animal studies indicate that notochord‐derived cells persist in the adult NP, the ontogeny of the adult human NP c...

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Dettagli Bibliografici
Pubblicato in:J Orthop Res
Autori principali: Rodrigues‐Pinto, Ricardo, Berry, Andrew, Piper‐Hanley, Karen, Hanley, Neil, Richardson, Stephen M., Hoyland, Judith A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5021113/
https://ncbi.nlm.nih.gov/pubmed/26910849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jor.23205
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