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Tiam–Rac signaling mediates trans-endocytosis of ephrin receptor EphB2 and is important for cell repulsion

Ephrin receptors interact with membrane-bound ephrin ligands to regulate contact-mediated attraction or repulsion between opposing cells, thereby influencing tissue morphogenesis. Cell repulsion requires bidirectional trans-endocytosis of clustered Eph–ephrin complexes at cell interfaces, but the me...

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Foilsithe in:J Cell Biol
Main Authors: Gaitanos, Thomas N., Koerner, Jorg, Klein, Ruediger
Formáid: Artigo
Teanga:Inglês
Foilsithe: The Rockefeller University Press 2016
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5021091/
https://ncbi.nlm.nih.gov/pubmed/27597758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201512010
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