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Dose‐escalation study of tabalumab with bortezomib and dexamethasone in Japanese patients with multiple myeloma

B‐cell activating factor (BAFF) promotes the survival and adhesion of multiple myeloma (MM) cells. Tabalumab (LY2127399) is an anti‐BAFF monoclonal antibody. This phase 1, multicenter, open‐label, nonrandomized, dose‐escalation study evaluated the safety, tolerability, pharmacokinetics, pharmacodyna...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Iida, Shinsuke, Ogiya, Daisuke, Abe, Yasunobu, Taniwaki, Masafumi, Asou, Hiroya, Maeda, Kaijiro, Uenaka, Kazunori, Nagaoka, Soshi, Ishiki, Tsuyoshi, Conti, Ilaria, Tobinai, Kensei
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5021044/
https://ncbi.nlm.nih.gov/pubmed/27350068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13000
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