Trichostatin A, a histone deacetylase inhibitor suppresses NADPH Oxidase 4‐Derived Redox Signalling and Angiogenesis

Histone deacetylase (HDAC) inhibitors are known to suppress abnormal development of blood vessels. Angiogenic activity in endothelial cells depends upon NADPH oxidase 4 (Nox4)‐dependent redox signalling. We set out to study whether the HDAC inhibitor trichostatin A (TSA) affects Nox4 expression and...

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Bibliographic Details
Published in:J Cell Mol Med
Main Authors: Hakami, Nora Y., Dusting, Gregory J., Peshavariya, Hitesh M.
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2016
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5020625/
https://ncbi.nlm.nih.gov/pubmed/27297729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12885
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