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Trp53 deficient mice predisposed to preterm birth display region-specific lipid alterations at the embryo implantation site
Here we demonstrate that conditional deletion of mouse uterine Trp53 (p53(d/d)), molecularly linked to mTORC1 activation and causally linked to premature uterine senescence and preterm birth, results in aberrant lipid signatures within the heterogeneous cell types of embryo implantation sites on day...
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| Udgivet i: | Sci Rep |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5020559/ https://ncbi.nlm.nih.gov/pubmed/27620843 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep33023 |
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