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Trp53 deficient mice predisposed to preterm birth display region-specific lipid alterations at the embryo implantation site

Here we demonstrate that conditional deletion of mouse uterine Trp53 (p53(d/d)), molecularly linked to mTORC1 activation and causally linked to premature uterine senescence and preterm birth, results in aberrant lipid signatures within the heterogeneous cell types of embryo implantation sites on day...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Lanekoff, Ingela, Cha, Jeeyeon, Kyle, Jennifer E., Dey, Sudhansu K., Laskin, Julia, Burnum-Johnson, Kristin E.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5020559/
https://ncbi.nlm.nih.gov/pubmed/27620843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep33023
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