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Chondroprotective effect of high-molecular-weight hyaluronic acid on osteoarthritic chondrocytes in a co-cultivation inflammation model with M1 macrophages

BACKGROUND: Osteoarthritis (OA) is described by an imbalance between anabolic and catabolic processes in the affected joint. This dysregulation of metabolism affects not only chondrocytes within cartilage tissue but also the cells of the synovial membrane across the border of the joint. An important...

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Pubblicato in:J Inflamm (Lond)
Autori principali: Bauer, Christoph, Niculescu-Morzsa, Eugenia, Jeyakumar, Vivek, Kern, Daniela, Späth, Stephan S., Nehrer, Stefan
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5020517/
https://ncbi.nlm.nih.gov/pubmed/27625590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12950-016-0139-y
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