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Recombination-driven generation of the largest pathogen repository of antigen variants in the protozoan Trypanosoma cruzi

BACKGROUND: The protozoan parasite Trypanosoma cruzi, causative agent of Chagas disease, depends upon a cell surface-expressed trans-sialidase (ts) to avoid activation of complement-mediated lysis and to enhance intracellular invasion. However these functions alone fail to account for the size of th...

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Detalhes bibliográficos
Publicado no:BMC Genomics
Main Authors: Weatherly, D. Brent, Peng, Duo, Tarleton, Rick L.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5020489/
https://ncbi.nlm.nih.gov/pubmed/27619017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-016-3037-z
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