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A Methionine Residue Promotes Hyperoxidation of the Catalytic Cysteine of Mouse Methionine Sulfoxide Reductase A
Methionine sulfoxide reductase A (msrA) reduces methionine sulfoxide in proteins back to methionine. Its catalytic cysteine (Cys72-SH) has a low pK(a) that facilitates oxidation by methionine sulfoxide to cysteine sulfenic. If the catalytic cycle proceeds efficiently, the sulfenic acid is reduced ba...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Biochemistry |
|---|---|
| Prif Awduron: | , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
2016
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5020372/ https://ncbi.nlm.nih.gov/pubmed/27259041 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b00180 |
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