Novel chlorambucil-conjugated anionic linear-globular PEG-based second-generation dendrimer: in vitro/in vivo improved anticancer activity

Evaluating the efficacy of anticancer drugs is an evolving and research-oriented issue. The objective of this study was to reduce the insolubility of chlorambucil (CBL) in water and improve the anticancer activity of CBL in vitro and in vivo through the conjugation of CBL with anionic linear-globula...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Onco Targets Ther
Main Authors: Assadi, Artin, Najafabadi, Vahideh Sharifi, Shandiz, Seyed Ataollah Sadat, Boroujeni, Azadah Shayeq, Ashrafi, Sepehr, Vaziri, Ali Zaman, Ghoreishi, Seyedeh Masoumeh, Aghasadeghi, Mohammad Reza, Ebrahimi, Seyed Esmaeil Sadat, Pirali-Hamedani, Morteza, Ardestani, Mehdi Shafiee
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2016
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5019448/
https://ncbi.nlm.nih.gov/pubmed/27660471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S103487
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados