The PU.1-Modulated MicroRNA-22 Is a Regulator of Monocyte/Macrophage Differentiation and Acute Myeloid Leukemia

MicroRNA-22 (miR-22) is emerging as a critical regulator in organ development and various cancers. However, its role in normal hematopoiesis and leukaemogenesis remains unclear. Here, we detected its increased expression during monocyte/macrophage differentiation of HL-60, THP1 cells and CD34(+) hem...

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Publicat a:PLoS Genet
Autors principals: Shen, Chao, Chen, Ming-Tai, Zhang, Xin-Hua, Yin, Xiao-Lin, Ning, Hong-Mei, Su, Rui, Lin, Hai-Shuang, Song, Li, Wang, Fang, Ma, Yan-Ni, Zhao, Hua-Lu, Yu, Jia, Zhang, Jun-Wu
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5019412/
https://ncbi.nlm.nih.gov/pubmed/27617961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006259
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