Self-assembled nanoparticles based on amphiphilic chitosan derivative and arginine for oral curcumin delivery

Curcumin (Cur) is a striking anticancer agent, but its low aqueous solubility, poor absorption, hasty metabolism, and elimination limit its oral bioavailability and consequently hinder its development as a drug. To redress these limitations, amphiphilic chitosan (CS) conjugate with improved mucoadhe...

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Bibliographic Details
Published in:Int J Nanomedicine
Main Authors: Raja, Mazhar Ali, Zeenat, Shah, Arif, Muhammad, Liu, Chenguang
Format: Artigo
Language:Inglês
Published: Dove Medical Press 2016
Subjects:
Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5019276/
https://ncbi.nlm.nih.gov/pubmed/27660435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S106116
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