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Promoter hypermethylation of KLOTHO; an anti-senescence related gene in colorectal cancer patients of Kashmir valley

Hypermethylation of CpG islands located in the promoter regions of genes is a major event in the development of the majority of cancer types, due to the subsequent aberrant silencing of important tumor suppressor genes. KLOTHO; a novel gene associated primarily with suppressing senescence has been s...

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Detalhes bibliográficos
Publicado no:Mol Biol Res Commun
Main Authors: Perveez, Malik, Ajaz, Malik, Afroze, Dil
Formato: Artigo
Idioma:Inglês
Publicado em: Shiraz University 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5019213/
https://ncbi.nlm.nih.gov/pubmed/27844013
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