Molecular evolutionary dynamics of cytochrome P450 monooxygenases across kingdoms: Special focus on mycobacterial P450s

Since the initial identification of cytochrome P450 monooxygenases (CYPs/P450s), great progress has been made in understanding their structure-function relationship, diversity and application in producing compounds beneficial to humans. However, the molecular evolution of P450s in terms of their dyn...

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Pubblicato in:Sci Rep
Autori principali: Parvez, Mohammad, Qhanya, Lehlohonolo Benedict, Mthakathi, Ntsane Trevor, Kgosiemang, Ipeleng Kopano Rosinah, Bamal, Hans Denis, Pagadala, Nataraj Sekhar, Xie, Ting, Yang, Haoran, Chen, Hengye, Theron, Chrispian William, Monyaki, Richie, Raselemane, Seiso Caiphus, Salewe, Vuyani, Mongale, Bogadi Lorato, Matowane, Retshedisitswe Godfrey, Abdalla, Sara Mohamed Hasaan, Booi, Wool Isaac, van Wyk, Mari, Olivier, Dedré, Boucher, Charlotte E., Nelson, David R., Tuszynski, Jack A., Blackburn, Jonathan Michael, Yu, Jae-Hyuk, Mashele, Samson Sitheni, Chen, Wanping, Syed, Khajamohiddin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5018878/
https://ncbi.nlm.nih.gov/pubmed/27616185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep33099
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