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Reassessment of long-term depression in cerebellar Purkinje cells in mice carrying mutated GluA2 C terminus

Long-term depression (LTD) of synaptic transmission from parallel fibers (PFs) to a Purkinje cell (PC) in the cerebellum has been considered to be a core mechanism of motor learning. Recently, however, discrepancies between LTD and motor learning have been reported in mice with a mutation that targe...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Yamaguchi, Kazuhiko, Itohara, Shigeyoshi, Ito, Masao
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5018784/
https://ncbi.nlm.nih.gov/pubmed/27551099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1609957113
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