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Autophagy and ubiquitin–proteasome system contribute to sperm mitophagy after mammalian fertilization

Maternal inheritance of mitochondria and mtDNA is a universal principle in human and animal development, guided by selective ubiquitin-dependent degradation of the sperm-borne mitochondria after fertilization. However, it is not clear how the 26S proteasome, the ubiquitin-dependent protease that is...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Song, Won-Hee, Yi, Young-Joo, Sutovsky, Miriam, Meyers, Stuart, Sutovsky, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5018771/
https://ncbi.nlm.nih.gov/pubmed/27551072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1605844113
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