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Regulatory evolution of Tbx5 and the origin of paired appendages

The diversification of paired appendages has been a major factor in the evolutionary radiation of vertebrates. Despite its importance, an understanding of the origin of paired appendages has remained elusive. To address this problem, we focused on T-box transcription factor 5 (Tbx5), a gene indispen...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Adachi, Noritaka, Robinson, Molly, Goolsbee, Aden, Shubin, Neil H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5018757/
https://ncbi.nlm.nih.gov/pubmed/27503876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1609997113
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