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Overproduction of reactive oxygen species - obligatory or not for induction of apoptosis by anticancer drugs

Many studies demonstrate that conventional anticancer drugs elevate intracellular level of reactive oxygen species (ROS) and alter redox-homeostasis of cancer cells. It is widely accepted that anticancer effect of these chemotherapeutics is due to induction of oxidative stress and ROS-mediated apopt...

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Bibliographische Detailangaben
Veröffentlicht in:Chin J Cancer Res
Hauptverfasser: Ivanova, Donika, Zhelev, Zhivko, Aoki, Ichio, Bakalova, Rumiana, Higashi, Tatsuya
Format: Artigo
Sprache:Inglês
Veröffentlicht: AME Publishing Company 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5018533/
https://ncbi.nlm.nih.gov/pubmed/27647966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21147/j.issn.1000-9604.2016.04.01
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