Glucagon-Like Peptide-1 Excites Firing and Increases GABAergic Miniature Postsynaptic Currents (mPSCs) in Gonadotropin-Releasing Hormone (GnRH) Neurons of the Male Mice via Activation of Nitric Oxide (NO) and Suppression of Endocannabinoid Signaling Pathways

Glucagon-like peptide-1 (GLP-1), a metabolic signal molecule, regulates reproduction, although, the involved molecular mechanisms have not been elucidated, yet. Therefore, responsiveness of gonadotropin-releasing hormone (GnRH) neurons to the GLP-1 analog Exendin-4 and elucidation of molecular pathw...

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Dettagli Bibliografici
Pubblicato in:Front Cell Neurosci
Autori principali: Farkas, Imre, Vastagh, Csaba, Farkas, Erzsébet, Bálint, Flóra, Skrapits, Katalin, Hrabovszky, Erik, Fekete, Csaba, Liposits, Zsolt
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2016
Soggetti:
Neuroscience
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5018486/
https://ncbi.nlm.nih.gov/pubmed/27672360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2016.00214
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