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Confidence intervals for the selected population in randomized trials that adapt the population enrolled

It is a challenge to design randomized trials when it is suspected that a treatment may benefit only certain subsets of the target population. In such situations, trial designs have been proposed that modify the population enrolled based on an interim analysis, in a preplanned manner. For example, i...

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Detalhes bibliográficos
Publicado no:Biom J
Autor principal: Rosenblum, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5018400/
https://ncbi.nlm.nih.gov/pubmed/23553577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bimj.201200080
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