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Weighted mutual information analysis substantially improves domain-based functional network models

Motivation: Functional protein–protein interaction (PPI) networks elucidate molecular pathways underlying complex phenotypes, including those of human diseases. Extrapolation of domain–domain interactions (DDIs) from known PPIs is a major domain-based method for inferring functional PPI networks. Ho...

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Foilsithe in:Bioinformatics
Main Authors: Shim, Jung Eun, Lee, Insuk
Formáid: Artigo
Teanga:Inglês
Foilsithe: Oxford University Press 2016
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5018372/
https://ncbi.nlm.nih.gov/pubmed/27207946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btw320
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