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Impacts of the G145R Mutation on the Structure and Immunogenic Activity of the Hepatitis B Surface Antigen: A Computational Analysis

BACKGROUND: Vaccine-escaped hepatitis B virus (HBV) mutations occur within the “a” determinant area, which is located in the major hydrophilic region (MHR) of the hepatitis B surface antigen (HBsAg) protein. It is now well established that the common G145R mutation is highly capable of escaping from...

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Библиографические подробности
Опубликовано в: :Hepat Mon
Главные авторы: Rezaee, Reza, Poorebrahim, Mansour, Najafi, Saeideh, Sadeghi, Solmaz, Pourdast, Alieh, Alavian, Seyed Moayed, Alavian, Seyed Ehsan, Poortahmasebi, Vahdat
Формат: Artigo
Язык:Inglês
Опубликовано: Kowsar 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5018363/
https://ncbi.nlm.nih.gov/pubmed/27642350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5812/hepatmon.39097
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