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The Conundrum of Genetic “Drivers” in Benign Conditions

Advances in deep genomic sequencing have identified a spectrum of cancer-specific passenger and driver aberrations. Clones with driver anomalies are believed to be positively selected during carcinogenesis. Accumulating evidence, however, shows that genomic alterations, such as those in BRAF, RAS, E...

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Detalhes bibliográficos
Publicado no:J Natl Cancer Inst
Main Authors: Kato, Shumei, Lippman, Scott M., Flaherty, Keith T., Kurzrock, Razelle
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5017937/
https://ncbi.nlm.nih.gov/pubmed/27059373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djw036
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