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Protection of α-CaMKII from Dephosphorylation by GluN2B Subunit of NMDA Receptor Is Abolished by Mutation of Glu(96) or His(282) of α-CaMKII

Interaction of CaMKII and the GluN2B subunit of NMDA receptor is essential for synaptic plasticity events such as LTP. Synaptic targeting of CaMKII and regulation of its biochemical functions result from this interaction. GluN2B binding to the T-site of CaMKII leads to changes in substrate binding a...

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Vydáno v:PLoS One
Hlavní autoři: Mayadevi, Madhavan, Lakshmi, Kesavan, Suma Priya, Sudarsana Devi, John, Sebastian, Omkumar, Ramakrishnapillai V.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5017783/
https://ncbi.nlm.nih.gov/pubmed/27610621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0162011
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