The Cytidine Analog Fluorocyclopentenylcytosine (RX-3117) Is Activated by Uridine-Cytidine Kinase 2

Fluorocyclopentenylcytosine (RX-3117) is an orally available cytidine analog, currently in Phase I clinical trial. RX-3117 has promising antitumor activity in various human tumor xenografts including gemcitabine resistant tumors. RX-3117 is activated by uridine-cytidine kinase (UCK). Since UCK exist...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Sarkisjan, Dzjemma, Julsing, Joris R., Smid, Kees, de Klerk, Daniël, van Kuilenburg, André B. P., Meinsma, Rutger, Lee, Young B., Kim, Deog J., Peters, Godefridus J.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5017758/
https://ncbi.nlm.nih.gov/pubmed/27612203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0162901
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker