Investigating the Effect of Ligand Amount and Injected Therapeutic Activity: A Simulation Study for (177)Lu-Labeled PSMA-Targeting Peptides

In molecular radiotherapy with (177)Lu-labeled prostate specific membrane antigen (PSMA) peptides, kidney and/or salivary glands doses limit the activity which can be administered. The aim of this work was to investigate the effect of the ligand amount and injected activity on the tumor-to-normal ti...

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Vydáno v:PLoS One
Hlavní autoři: Kletting, Peter, Schuchardt, Christiane, Kulkarni, Harshad R., Shahinfar, Mostafa, Singh, Aviral, Glatting, Gerhard, Baum, Richard P., Beer, Ambros J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2016
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5017739/
https://ncbi.nlm.nih.gov/pubmed/27611841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0162303
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