Phenotypic and Molecular Alterations in the Mammary Tissue of R-Spondin1 Knock-Out Mice during Pregnancy

R-spondin1 (Rspo1) is a member of a secreted protein family which has pleiotropic functions in development and stem cell growth. Rspo1 knock-out mice are sex-reversed, but some remain sub-fertile, so they fail to nurse their pups. A lack of Rspo1 expression in the mammary gland results in an absence...

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Publicat a:PLoS One
Autors principals: Chadi, Sead, Polyte, Jacqueline, Lefevre, Lucas, Castille, Johan, Ehanno, Aude, Laubier, Johann, Jaffrézic, Florence, Le Provost, Fabienne
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5017653/
https://ncbi.nlm.nih.gov/pubmed/27611670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0162566
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