Immunoglobulin G4(+) B‐cell receptor clones distinguish immunoglobulin G 4‐related disease from primary sclerosing cholangitis and biliary/pancreatic malignancies

Immunoglobulin G4 (IgG4)‐related disease (IgG4‐RD) of the biliary tree and pancreas is difficult to distinguish from sclerosing cholangitis and biliary/pancreatic malignancies (CA). An accurate noninvasive test for diagnosis and monitoring of disease activity is lacking. We demonstrate that dominant...

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Veröffentlicht in:Hepatology
Hauptverfasser: Doorenspleet, Marieke E., Hubers, Lowiek M., Culver, Emma L., Maillette de Buy Wenniger, Lucas J., Klarenbeek, Paul L., Chapman, Roger W., Baas, Frank, van de Graaf, Stan F., Verheij, Joanne, van Gulik, Thomas M., Barnes, Eleanor, Beuers, Ulrich, de Vries, Niek
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2016
Schlagworte:
Autoimmune, Cholestatic and Biliary Disease
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5017301/
https://ncbi.nlm.nih.gov/pubmed/27015613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.28568
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