Glycyrrhizin protects against focal cerebral ischemia via inhibition of T cell activity and HMGB1-mediated mechanisms

BACKGROUND: Glycyrrhizin (Gly) protects against brain injury induced by stroke. We studied whether Gly achieves its protection by inhibiting T cell activity and high-mobility group box 1 (HMGB1) release in the ischemic brain. METHODS: Stroke was induced by transient middle cerebral artery occlusion...

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Vydáno v:J Neuroinflammation
Hlavní autoři: Xiong, Xiaoxing, Gu, Lijuan, Wang, Yan, Luo, Ying, Zhang, Hongfei, Lee, Jessica, Krams, Sheri, Zhu, Shengmei, Zhao, Heng
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2016
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5016958/
https://ncbi.nlm.nih.gov/pubmed/27609334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-016-0705-5
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