Contribution of type W human endogenous retroviruses to the human genome: characterization of HERV-W proviral insertions and processed pseudogenes

BACKGROUND: Human endogenous retroviruses (HERVs) are ancient sequences integrated in the germ line cells and vertically transmitted through the offspring constituting about 8 % of our genome. In time, HERVs accumulated mutations that compromised their coding capacity. A prominent exception is HERV-...

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Veröffentlicht in:Retrovirology
Hauptverfasser: Grandi, Nicole, Cadeddu, Marta, Blomberg, Jonas, Tramontano, Enzo
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2016
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Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5016936/
https://ncbi.nlm.nih.gov/pubmed/27613107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12977-016-0301-x
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