Prokineticin 2 antagonist, PKRA7 suppresses arthritis in mice with collagen-induced arthritis

BACKGROUND: Prokineticin 2 (PK2) expression is upregulated in mice with collagen-induced arthritis (CIA), an animal model of rheumatoid arthritis. The purpose of our study was to investigate the effects of PK2 inhibition on CIA. METHODS: PK2, prokineticin receptor (PKR) 1, and PKR2 mRNA transcripts...

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Bibliografske podrobnosti
izdano v:BMC Musculoskelet Disord
Main Authors: Ito, Haruyasu, Noda, Kentaro, Yoshida, Ken, Otani, Kazuhiro, Yoshiga, Masayuki, Oto, Yohsuke, Saito, Saburo, Kurosaka, Daitaro
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2016
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5016855/
https://ncbi.nlm.nih.gov/pubmed/27609223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12891-016-1243-0
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