Structure of the Single-lobe Myosin Light Chain C in Complex with the Light Chain-binding Domains of Myosin-1C Provides Insights into Divergent IQ Motif Recognition

Myosin light chains are key regulators of class 1 myosins and typically comprise two domains, with calmodulin being the archetypal example. They bind IQ motifs within the myosin neck region and amplify conformational changes in the motor domain. A single lobe light chain, myosin light chain C (MlcC)...

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Publicado en:J Biol Chem
Autores principales: Langelaan, David N., Liburd, Janine, Yang, Yidai, Miller, Emily, Chitayat, Seth, Crawley, Scott W., Côté, Graham P., Smith, Steven P.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2016
Materias:
Protein Structure and Folding
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5016694/
https://ncbi.nlm.nih.gov/pubmed/27466369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.746313
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