Secreted Protein Acidic and Rich in Cysteine (SPARC) Mediates Metastatic Dormancy of Prostate Cancer in Bone

Prostate cancer is known to frequently recur in bone; however, how dormant cells switch its phenotype leading to recurrent tumor remains poorly understood. We have isolated two syngeneic cell lines (indolent and aggressive) through in vivo selection by implanting PC3mm stem-like cells into tibial bo...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Sharma, Sambad, Xing, Fei, Liu, Yin, Wu, Kerui, Said, Neveen, Pochampally, Radhika, Shiozawa, Yusuke, Lin, Hui-Kuan, Balaji, K. C., Watabe, Kounosuke
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2016
Fag:
Cell Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5016675/
https://ncbi.nlm.nih.gov/pubmed/27422817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.737379
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