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Clinically relevant RHD-CE genotypes in patients with sickle cell disease and in African Brazilian donors

BACKGROUND: As a consequence of the homology and opposite orientation of RHD and RHCE, numerous gene rearrangements have occurred in Africans and resulted in altered RH alleles that predict partial antigens, contributing to the high rate of Rh alloimmunisation among patients with sickle cell disease...

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Detalhes bibliográficos
Publicado no:Blood Transfus
Main Authors: Gaspardi, Ane C., Sippert, Emília A., de Macedo, Mayra Dorigan, Pellegrino, Jordão, Costa, Fernando F., Castilho, Lilian
Formato: Artigo
Idioma:Inglês
Publicado em: Edizioni SIMTI - SIMTI Servizi Srl 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5016305/
https://ncbi.nlm.nih.gov/pubmed/27177398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2450/2016.0275-15
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