Imaging and cerebrospinal fluid biomarkers in early preclinical Alzheimer disease

OBJECTIVE: Deposition of Aβ-containing plaques as evidenced by amyloid imaging and CSF Aβ42 is an early indicator of preclinical Alzheimer disease (AD). To better understand their relationship during the earliest preclinical stages, we investigated baseline CSF markers in cognitively normal individu...

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Veröffentlicht in:Ann Neurol
Hauptverfasser: Vlassenko, Andrei G., McCue, Lena, Jasielec, Mateusz S, Su, Yi, Gordon, Brian A., Xiong, Chengjie, Holtzman, David M, Benzinger, Tammie LS, Morris, John C, Fagan, Anne M
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5016232/
https://ncbi.nlm.nih.gov/pubmed/27398953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.24719
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