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Epigenetic Plasticity Drives Adipogenic and Osteogenic Differentiation of Marrow-derived Mesenchymal Stem Cells

Terminal differentiation of multipotent stem cells is achieved through a coordinated cascade of activated transcription factors and epigenetic modifications that drive gene transcription responsible for unique cell fate. Within the mesenchymal lineage, factors such as RUNX2 and PPARγ are indispensab...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Main Authors: Meyer, Mark B., Benkusky, Nancy A., Sen, Buer, Rubin, Janet, Pike, J. Wesley
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5016174/
https://ncbi.nlm.nih.gov/pubmed/27402842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.736538
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