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The Plasma Membrane Protein Nce102 Implicated in Eisosome Formation Rescues a Heme Defect in Mitochondria

The cellular transport of the cofactor heme and its biosynthetic intermediates such as protoporphyrin IX is a complex and highly coordinated process. To investigate the molecular details of this trafficking pathway, we created a synthetic lesion in the heme biosynthetic pathway by deleting the gene...

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Détails bibliographiques
Publié dans:J Biol Chem
Auteurs principaux: Kim, Hyung J., Jeong, Mi-Young, Parnell, Timothy J., Babst, Markus, Phillips, John D., Winge, Dennis R.
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5016138/
https://ncbi.nlm.nih.gov/pubmed/27317660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.727743
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