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Testing for oncogenic molecular aberrations in cell-free DNA-based liquid biopsies in the clinic: are we there yet?

The optimal choice of cancer therapy depends upon analysis of the tumor genome for druggable molecular alterations. The spatial and temporal intratumor heterogeneity of cancers creates substantial challenges, as molecular profile depends on time and site of tumor tissue collection. To capture the en...

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Detalhes bibliográficos
Publicado no:Expert Rev Mol Diagn
Main Authors: Polivka, Jiri, Pesta, Martin, Janku, Filip
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5016094/
https://ncbi.nlm.nih.gov/pubmed/26559503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1586/14737159.2015.1110021
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