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Stochastic multi-scale models of competition within heterogeneous cellular populations: Simulation methods and mean-field analysis

We propose a modelling framework to analyse the stochastic behaviour of heterogeneous, multi-scale cellular populations. We illustrate our methodology with a particular example in which we study a population with an oxygen-regulated proliferation rate. Our formulation is based on an age-dependent st...

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Veröffentlicht in:J Theor Biol
Hauptverfasser: Cruz, Roberto de la, Guerrero, Pilar, Spill, Fabian, Alarcón, Tomás
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5016039/
https://ncbi.nlm.nih.gov/pubmed/27457092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtbi.2016.07.028
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