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De Novo Herpes Simplex Virus VP16 Expression Gates a Dynamic Programmatic Transition and Sets the Latent/Lytic Balance during Acute Infection in Trigeminal Ganglia

The life long relationship between herpes simplex virus and its host hinges on the ability of the virus to aggressively replicate in epithelial cells at the site of infection and transport into the nervous system through axons innervating the infection site. Interaction between the virus and the sen...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Sawtell, Nancy M., Thompson, Richard L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5015900/
https://ncbi.nlm.nih.gov/pubmed/27607440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005877
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