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Translation Regulation and RNA Granule Formation after Heat Shock of Procyclic Form Trypanosoma brucei: Many Heat-Induced mRNAs Are also Increased during Differentiation to Mammalian-Infective Forms

African trypanosome procyclic forms multiply in the midgut of tsetse flies, and are routinely cultured at 27°C. Heat shocks of 37°C and above result in general inhibition of translation, and severe heat shock (41°C) results in sequestration of mRNA in granules. The mRNAs that are bound by the zinc-f...

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Detalhes bibliográficos
Publicado no:PLoS Negl Trop Dis
Main Authors: Minia, Igor, Merce, Clementine, Terrao, Monica, Clayton, Christine
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5015846/
https://ncbi.nlm.nih.gov/pubmed/27606618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0004982
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