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National Prociency Testing Result of CYP2D6*10 Genotyping for Adjuvant Tamoxifen Therapy in China

Tamoxifen has been successfully used for treating breast cancer and preventing cancer recurrence. Cytochrome P450 2D6 (CYP2D6) plays a key role in the process of metabolizing tamoxifen to its active moiety, endoxifen. Patients with variants of the CYP2D6 gene may not receive the full benefit of tamo...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Lin, Guigao, Zhang, Kuo, Yi, Lang, Han, Yanxi, Xie, Jiehong, Li, Jinming
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5015788/
https://ncbi.nlm.nih.gov/pubmed/27603206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0162361
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