Modeling ALS using motor neurons derived from human induced pluripotent stem cells

Directing the differentiation of induced pluripotent stem cells into motor neurons has allowed investigators to develop novel models of ALS. However, techniques vary between laboratories and the cells do not appear to mature into fully functional adult motor neurons. Here we discuss common developme...

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Detalhes bibliográficos
Publicado no:Nat Neurosci
Main Authors: Sances, S, Bruijn, LI, Chandran, S, Eggan, K, Ho, R, Klim, J, Livesey, MR, Lowry, E, Macklis, JD, Rushton, D, Sadegh, C, Sareen, D, Wichterle, H, Zhang, SC, Svendsen, CN
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5015775/
https://ncbi.nlm.nih.gov/pubmed/27021939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.4273
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