A carregar...

Novel small molecule binders of human N-glycanase 1, a key player in the endoplasmic reticulum associated degradation pathway

Peptide:N-glycanase (NGLY1) is an enzyme responsible for cleaving oligosaccharide moieties from misfolded glycoproteins to enable their proper degradation. Deletion and truncation mutations in this gene are responsible for an inherited disorder of the endoplasmic reticulum-associated degradation pat...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Bioorg Med Chem
Main Authors: Srinivasan, Bharath, Zhou, Hongyi, Mitra, Sreyoshi, Skolnick, Jeffrey
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5015769/
https://ncbi.nlm.nih.gov/pubmed/27567076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2016.08.019
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!