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αB-crystallin: Portrait of a malignant chaperone as a cancer therapeutic target
αB-crystallin is a widely expressed member of the small heat shock protein family that protects cells from stress by its dual function as a molecular chaperone to preserve proteostasis and as a cell death antagonist that negatively regulates components of the conserved apoptotic cell death machinery...
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| Publicado no: | Pharmacol Ther |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5015648/ https://ncbi.nlm.nih.gov/pubmed/26820756 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharmthera.2016.01.012 |
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